The Seminole Casino Hotel is Southwest Florida's top destination for slots and live blackjack. . But no need to worry, there are some fantastic surrounding casinos, particularly Bonita Springs Napoli Fort Myers Casino, Seminole Casino Hotel Immokalee. Browse our selection of 4 Casino hotels & resorts in Naples, FL for the ultimate stay & play vacation. With an array of slot machines and live table games, there are. Make your casino vacation a sure bet with Expedia and.